Headspace Sampler HS-10

Cost-Efficient Model Equipped with the Functions Needed for Headspace Analysis

Residual solvents in pharmaceuticals are strictly controlled, and are categorized as Class 1 to Class 3 depending on the risk they pose to human health. The headspace GC method prescribed in USP <467> is utilized for the analysis of residual solvents. Class 1 Procedure A requires a S/N ratio ≥5 for 1,1,1-trichloroethane and a S/N ratio ≥3 for all peaks, while Class 2A requires a resolution ≥1.0 for acetonitrile and methylene chloride. The HS-10 satisfies all of these requirements.

The HS-10 headspace sampler is highly cost efficient, yet is equipped with advanced features such as a mixing function and the ability to heat-ahead the sample vials waiting for analysis. This instrument is the perfect platform for the analysis of residual pharmaceutical solvents and trace VOCs in wastewater.


Outstanding Reproducibility

Favorable area reproducibility can be obtained, thanks to high-accuracy flow rate control by electronic flow controllers (AFC and APC), and a thermostatic vial chamber with a uniform temperature distribution.

The temperature in the thermostatic vial chamber is uniform; as a result, there is no variance in gas-liquid equilibrium depending on intake position.

Reproducibility for 0.4 % Ethanol 2.0 % (n = 10)

Overlap Analysis

During a GC analysis, the HS-10 will take the next vial and move it to the vial heater. There, it can incubate for a specified time and be ready for injection when the previous analysis cycle has ended.

Mixing Function

The HS-10 is equipped with the ability to mix each vial by shaking. This allows the headspace concentration within each sample to come to equilibrium sooner, ultimately saving time and increasing throughput.

Vials are mixed by moving them up and down.

Compatible with the LabSolutions Comprehensive Workstation

LabSolutions LC/GC software integrates the conventional programs LCsolution and GCsolution. With a user control function and an audit trail function for method parameters, LabSolutions can accommodate a variety of regulations, including directives related to FDA 21 CFR Part 11.

For Research Use Only. Not for use in diagnostic procedures.
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