
Pharmaceutical History
This timeline outlines the development of Shimadzu's Pharmaceutical Solutions products over the past 150 years. Each entry reflects Shimadzu's commitment to advancing sensitivity, speed, and usability in analytical chemistry. From the introduction of the first Pharmaceutical Solutions system to the latest innovations, Shimadzu has made significant contributions to various fields, including pharmaceutical research, proteomics, and environmental analysis.
The integrators offered easy and reproducible data processing using the Chromatopac integration algorithm, which is kept in our chromatography software until today.
LC-6A HPLC system introduced for higher performance and modular configuration.
UV-160 spectrophotometer introduced for precise, reliable UV/VIS analysis.
LC-10A system featured fiber optic interface for improved detector connection.
Introduction of MALDI Benchtop instruments, expanding capabilities in mass spectrometry.
Launch of TOC-5000A for advanced total organic carbon analysis.
Discovery VP with advanced control system for automated HPLC.
Compact TOC-4000 analyzer for environmental applications.
Software introduced for 21 CFR Part 11 compliance in laboratories.
Compact all-in-one LC system for efficient operation.
The modular LC system offered several pump options and detectors and control by a web Interface. Software drivers for compatiblity to other vendors CDS systems were developed.
System for comprehensive trapping and recovery in chromatography.
Network-compatible data system enabling compliance and central management.
World’s first imaging mass microscope combining optical and MS imaging.
Compact LC systems evolving through the years with higher automation.
First-ever fully automated SFC/UHPLC system integrating liquid chromatography.
Intelligent Nexera series with IoT, auto-diagnostics, and AI.
Preparative SFC system for high-purity compound isolation.
Method development support software to accelerate workflows.
Ultra-fast purification system designed for biopharmaceutical research.
Throughout its 150-year history, Shimadzu has gathered numerous stories that exemplify its role in the advancement of analytical technology. Each narrative reflects the contributions of individuals and the evolution of innovations across various fields. Below, we present some of these stories that highlight key milestones in our journey and the impact they have had.
In recent years, oligonucleotide-based medicines have been recognized for their potential as new treatments for rare and chronic diseases and several new drugs have been approved by regulatory agencies. Analysis of these nucleic acid polymers to confirm identity and purity by LC-MS is a challenge, as they possess several reactive groups that can lead to adsorption onto metal surfaces in a stainless-steel-based UHPLC instrument. This article introduces the improvement of quantitative performance in the LC-MS analysis of oligonucleotides using the Nexera XS inert, a bioinert UHPLC system.
Chemicals such as herbicides, fungicides, insecticides and seed treatments are widely used to maximize crop yields worldwide. Ensuring the efficacy and safety of products requires studying the formulations in detail, including even the most minor of components. In this article, we talk to Syngenta about how they’re using Shimadzu’s UFPLC systems to speed up the extraction and purification of gram quantities of by-products that are present in technical-grade active-ingredient material at levels below1 %, so providing the material needed for regulatory tests and toxicity studies.
How can you accelerate the development of therapeutic drug candidates while also reducing their cost? The global AI-driven precision medicine company Exscientia in Oxford, UK, might have the answer. By integrating AI and machine-learning in its discovery process, Exscientia has been able to generate new molecules far faster than with conventional methods and has already delivered compounds into clinical development. Exscientia’s scientists explain this new approach and how their recent collaboration with Shimadzu helped further automate the discovery process to synthesize and purify new drug candidates in superfast time.
Are you interested in our Pharma products? You can explore them up close at various upcoming events. Our experts will be available to answer any questions you may have. We look forward to seeing you there!
The Nexera™ UC Prep is a semi preparative supercritical fluid chromatography (SFC) system that offers both the high basic performance developed for the previous Nexera UC model and original state-of-the-art preparative SFC technologies.
i-Series
The new, integrated i-Series LC system maintains the excellent performance of its predecessor while addressing the need for automation efficiency.
UV-1900i
Experience unmatched precision and ease with UV-1900i Plus. Featuring a refined user-friendly interface, ultra high-speed scanning, and comprehensive support functions, UV-1900i Plus ensures accurate and efficient measurements for all your needs.
Nexis GC-2050
The Gas Chromatograph Brevis GC-2050 has been fully updated, -compact, powerful, and cost-efficient- crafted to elevate your productivity to unprecedented levels.
Lab Solution MD
LabSolutions MD uses an “Analytical Quality by Design” (AQbD) approach for achieving efficient method development by designing analysis methods based on science and risk.